One is that he talks about how important it was to get away from dark corridor shooters with monsters jumping out at you, and yet - you can watch the main gameplay trailer they've released and admire all the ... dark corridors with monsters jumping out at you.
But the main thing that made me go "huh?" is when he's talking about how they need to avoid redoing the entire engine for every game, and what they might save development time on in the future, he says something like "the AI, the animation, is basically good enough" (so they wouldn't be changed for future games).
Uh, what? Maybe if you want to make games where mindless monsters pop out on scripted paths and they animate around awkwardly and unnaturally, then yes, AI and animation are done, but in a more general sense, then no, they're not even remotely close. Time would be much better spent if they never rev'ed the graphics engine again and instead focused on AI and animation.
Valve is a good example; their graphics engine is actually pretty archaic now, but their animation system is very good, and their games look great because of it. Motion is hugely important; and of course valve's animation is still way behind where it should be (animation needs to become more code-driven, less canned, so that it can be more dynamic to weight transfer and surface and other world interactions, and also just more varied, more emotional). I think motion is maybe the most important step in the uncanny valley. If you have very natural motion even on a stick figure it looks startlingly real.
(Valve's characters still look like puppets that play one animation, then the next, sort of like the mechatronic Country Bear Jamboree kind of thing; they're very clever to use robots or toon shading to hide the uncanny valley).
Nobody is even close on AI. I don't expect game AI's that can talk to you or learn, but the goal should be very simple : playing a networked game against AI's should be just as fun as playing against humans. This is the "Turing test" for game AI if you like; if you shut off voice chat and play your Halo or Starcraft or whatever vs. an opponent and don't get told if it's AI or human, you shouldn't be able to tell. The AI should surprise you and experiment and sometimes make mistakes and make you laugh and impress you and do all those things that humans can do. Of course it should be able to, our sights are way too low.
Software developers often get stuck in the abstraction, they wind up comparing to their peers and forget about the absolute target.