Myrhvold back in the day was one of the "gunslingers" at the top of Microsoft who was responsible for their highly immoral and sometimes illegal practices, which consisted of vaporware announcements, exclusivity deals, and general bullying to sabotage any attempts at free market competition in computers. (see here for example). It's hard for me to get back in that mindset now, Microsoft seems so inept these days, but let's not forget it was built on threats, lies, bullying, and stealing (I assume this was mostly Bill's doing).
Nowadays, Nathan Myhrvold is basically enemy #1 if you believe that most patents are evil.
His "Intellectual Ventures" is basically buying up every patent they think they can make money on, and then extracting license fees. He talks a lot of shit about funding invention, but that is an irrelevant facade to hide what they're really doing, which is buying up patents and then forcing people to license under threat of suit.
Even if you support patents you must see that innovation is being stifled because tech startups have to live in fear that the completely obvious algorithm they implemented was patented by some someone, and was then bought by some fund that has a team of lawyers hunting for infringers.
The Coalition for Patent Fairness has been doing some decent work at making small steps towards reform. The CPF is big business and certainly not revolutionary anti-patentites, they just want it to be a bit harder for someone to patent something absurd like "one click ordering" and then to extract huge damages for it. And of course Myhrvold is against them.